Brendan Canning, PhD
Dr. Brendan J. Canning, Ph.D. is a Professor of Medicine at The Johns Hopkins University School of Medicine in Baltimore, Maryland. He joined the Division of Allergy and Clinical Immunology of the Department of Medicine in 1996. He has been or is currently Co-Editor-in-Chief or Associate Editor for six medical research journals. Dr. Canning has served as a scientific advisory board member and a consultant for many pharmaceutical and biotech companies. His research is sponsored by grants from the NIH and by collaborations with industry. Research in the Canning Lab is focused on mechanistic studies of the cough reflex. Through their work, they identified the afferent nerves that play an essential role in regulating cough. The lab has also been characterizing the CNS pathways regulating the cough reflex and interactions amongst various afferent nerve subtypes in regulating cough. The team has identified key sites of integration of airway afferent nerve input and mechanisms by which afferent nerve subtypes act synergistically to regulate cough. The experimental approaches include electrophysiological recordings, CNS microinjection techniques, in vivo preparations for monitoring cough and reflex bronchospasm, neuronal tracing and immunohistochemistry.
