Platform
Traditional brain medications often caused side effects due to a lack of understanding about disease pathways. Our development platform draws upon our unique competency in understanding the circuitry of the brain and novel business approaches.
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Unprecedented visibility into neuroscience
Our team have been leaders in using high-throughput genomic approaches to understanding brain function in health and in disease. We have published our insights in the best scientific journals such as Science, the New England Journal of Medicine, Cell, and Neuron, and have led international consortia of scientists to develop these new insights to guide therapy development
A track record of developing new paradigms
Our team has consistently changed the game – from pioneering direct to consumer genomics to reduce the burden of chronic disease, to inventing cancer tumor sequencing to assign chemotherapy correctly, to modifying the human microbiome to address numerous diseases – we build new solutions to benefit patients.
Target-driven therapeutic molecule identification
Our drug discovery method prioritizes finding existing compounds with the right fit ("selectivity") to target the cough reflex pathway. This worldwide search leverages various data sources to find a suitable pre-existing molecule, significantly speeding up initial development stages.
Acceleration through clinical data
Knowing the precise target at the core of the disease process against which to aim a therapy is crucial to develop highly effective and safe therapies. Our target identification efforts in chronic cough led us to identify a central node in the circuit that controls the human cough reflex – a process essential for life.